Represented on the ISE Executive Committee by JES Vice-President, Takashi Akamizu of Wakayama Medical University, JES is a leading member of the ISE as the world's second oldest academic society in endocrinology and pioneers in global research.

The Kobe Declaration was signed at the Commemorative Event on Friday November 24, 2017. It states in the ten-year lead up to JES's 100th anniversary, the Society will strive to:
- Provide accurate information to the public and promote awareness on hormones and hormone-related disorders to achieve early diagnosis and treatment.
- Provide up-to-date guidelines to all patients with endocrine and metabolic disorders, assign the specialists properly, and promote sound inter-regional cooperation to meet nationwide medical needs in endocrinology and metabolism.
- Train genuine experts in endocrinology and metabolism who have a well-rounded knowledge on endocrinology, which is the basis for all life-course phenomena, and who take delight and pride in contributing to all areas of medical science.
- Support research to elucidate the mechanisms of the pathophysiology of endocrine and metabolic disorders, discover new hormones, and apply these findings to medical practice.
- Take initiative and guide global action on endocrinology with flexible responses to new trends of endocrinology caused by changes in lifestyles and the environment and the rapid aging of society.